… for assembly of such gene transfer system, the potential of modified silica nanoparticles
as a … Silica nanoparticles modified with aminosilanes as carriers for plasmid DNA. Int J …

… , but functional modification of the carriers may affect their gene … Plasmid DNA (pEGFP-C1)
in buffer solutions were mixed … was lower than the intrinsic pK a of aminosilane (∼9.8) [47]. It …

… Silica-based nanoparticles are promising carriers for gene … was the aminosilanemodified
solid silica nanoparticles with … capacity toward negatively charged plasmid DNA (pDNA) and …

… a surface modification with amino-silanes and further … ], few are about silica particles as gene
carriers. One of them … non-porous silica nanoparticles and modified them with amine groups …

… In order to avoid such problems the surface of the nanoparticles was modified with silica,
aminosilane, chitosan and Tris. The use of such capping agents provides stabilization of …

… Mesoporous silica (MPS) is an excellent carrier because of its … amino modification on MCM-41
for adsorption of plasmid DNA (… functionalized by diverse aminosilane coupling reagents. …

… new pores and attaching to carrier proteins and ion channels… -48-type nanoparticles)
functionalized with aminosilane were linked … In this review, mesoporous silica nanoparticles can …

… recognition tools and targeted drug delivery carriers [86, 87]. … , aminosilane-coated MNPs
interact with the polyanionic DNA … The structure of plasmid DNA provides some advantages …

… for the synthesis and co-modification of mesoporous silica nanoparticles (MSNs) with various
… silica nanoparticles as controlled release drug delivery and gene transfection carriers. …

… fragments, thus improving the adsorption efficiency of the DNA fragments. However, these
modified silica matrices are still hardly applied in size-selective separation of DNA fragments. …